Theodore (Zhengde) Zhao' Homepage

About Me

I am a Senior Applied Scientist at Microsoft, Health and Life Sciences Research. Currently, I focus on creating state of the art foundation models for healthcare AI. Some of my recent work include:

Large Multimodal Foundation Model: Image Analysis, Segmentation, Generation
Machine Learning: Time Series, Self-Superversion, LLM Error Detection, Multiscale analysis
LLMs For Healthcare: Cancer Diagnosis and Staging

I received my PhD and Master degrees in Applied Mathematics from University of Washington , advised by Prof. Tim Leung. I also worked at Microsoft, Harborview Medical Center, Rotella Capital Management, and Parametric as an Intern. I received my Bachelor degree in Physics from Fudan University in Shanghai, China.

News

[Nov. 2024] BiomedPrase is in Nature Methods! We are also releasing the code, model, and a million scale text promptable medical image segmentation dataset.
[May. 2024] Proud to lead the BiomedPrase project. We presented a foundation model for joint segmentation, detection and recognition of biomedical objects across nine modalities. Various medical image analysis tasks are unified with natural language prompting.
[May. 2024] Our paper on LLM Error Detection is accepted by ACL 2024. See you in Bangkok!
[April. 2024] I am giving a talk at 2024 Joint Statistical Meetings on 08/05/2024 in Portland.

Recent Works

A foundation model for joint segmentation, detection and recognition of biomedical objects across nine modalities

Theodore Zhao, Yu Gu, Jianwei Yang, Naoto Usuyama, Ho Hin Lee, Sid Kiblawi, Tristan Naumann, Jianfeng Gao, Angela Crabtree, Jacob Abel, Christine Moung-Wen, Brian Piening, Carlo Bifulco, Mu Wei, Hoifung Poon, Sheng Wang

Nature Methods, 2024
[PAPER] [DEMO] [BLOG] [CODE] [MODEL] [DATA]

We propose BiomedParse, a biomedical foundation model that can jointly conduct segmentation, detection and recognition across nine imaging modalities.
Pareto Optimal Learning for Estimating Large Language Model Errors

Theodore Zhao, Mu Wei, J Samuel Preston, Hoifung Poon

ACL, 2024
[PDF]

We utilized Pareto optimal ledarning to estimate LLM error and increase the performance, surpassing state-of-the-art task specific models.
Foundation Models for Biomedical Image Segmentation: A Survey

Ho Hin Lee, Yu Gu, Theodore Zhao, Yanbo Xu, Jianwei Yang, Naoto Usuyama, Cliff Wong, Mu Wei, Bennett A Landman, Yuankai Huo, Alberto Santamaria-Pang, Hoifung Poon

Preprint, 2024
[PDF]

We examine the adaptations and integrations of SAM necessary to address longstanding clinical challenges, in the context of 33 open datasets covered in our analysis.
A Noisy Fractional Brownian Motion Model for Multiscale Correlation Analysis of High-Frequency Prices

Tim Leung*, Theodore Zhao*

Mathematics, 2024

We analyze the multiscale behaviors of high-frequency intraday prices, with a focus on how asset prices are correlated over different timescales.
Fee for home delivery and monitoring of antiretroviral therapy for HIV infection compared with standard clinic-based services in South Africa: a randomised controlled trial

Ruanne V Barnabas, Adam A Szpiro, Xolani Ntinga, Melissa Latigo Mugambi, Heidi van Rooyen, Andrew Bruce, Philip Joseph, Thulani Ngubane, Meighan L Krows, Torin T Schaafsma, Theodore Zhao, Frank Tanser, Jared M Baeten, Connie Celum, Alastair van Heerden, Siyabonga Nkala

The Lancet HIV, 2022

We conducted a randomised trial, the Deliver Health Study, of a fee for home delivery of ART compared d with free clinic ART delivery in South Africa.
Financial time series analysis and forecasting with Hilbert–Huang transform feature generation and machine learning
Tim Leung*, Theodore Zhao*

Applied Stochastic Models in Business and Industry, 2021
[PDF]

We present the method of complementary ensemble empirical mode decomposition (CEEMD) and Hilbert-Huang transform (HHT) for analyzing nonstation financial time series.

Misc

In my free time, I love stargazing. I also started making my own music recently.

Here are some of my music — Just a heads-up, you'll hear real SOUND when you hit “play”! 🎵 🎧

For Nora: Entanglement

For Parents' 30th Anniversary: Pearl Waltz

For Dad: À La Recherche Du Temps Perdu

For Mom: Sunshine in the Winter

If my research/music interests you, send me an email! I'm always open to collaborations and discussions.🍺